In this nationwide register-based study, excess mortality among persons with schizophrenia was clearly observed. Regional variations in SMRs were not associated with population characteristics or psychiatric health care resources of a hospital district. Total mortality, circulatory deaths, and suicides differed among the 20 hospital districts examined. In natural causes of death, the SMR for ill-defined and unknown causes of death was almost 25. The largest single unnatural cause of death was suicide. The SMRs for all-cause mortality, circulatory system diseases, and suicides were higher for females than males in almost all age groups. They had 4.45-fold higher mortality than the general population, and patients' mortality was significantly elevated in all age groups. Standardized mortality ratios (SMRs) were calculated by matching patients' data with the general Finnish population on age, gender, and place of residence.ĭuring the five-year follow-up of 7,591 schizophrenia patients, 403 (5%) patients died. This was a nationwide register-based five-year follow-up study of all patients with onset of schizophrenia between 19.
This study analyzed gender-specific mortality of patients with a first episode of schizophrenic illness, particularly deaths from circulatory system diseases and suicide.
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